Skip to main content

Signs and symptoms of ADPKD

Autosomal dominant polycystic kidney disease (ADPKD) often presents as nonspecific symptoms, so many people may actually live with ADPKD for years before this kidney condition is recognized1

Even though ADPKD is a hereditary disease, family history may be unknown, and patients may not see a link between symptoms and the disease.2

Having a first occurrence of hypertension, pain, infection, or hematuria is one of the most important predictive indicators of rapid progression of ADPKD.2

Initial signs or symptoms associated with ADPKD can include1,2:

The benefits of early intervention

Earlier detection and management of ADPKD may provide the opportunity for interventions to treat early onset hypertension and cardiovascular complications, cyst infection, and nephrolithiasis.2,3

  1. Harris PC, Torres VE. Polycystic kidney disease. Annu Rev Med. 2009;60:321-337.

  2. Ness B, Stovall K. Current recommendations for treating autosomal dominant polycystic kidney disease. JAAPA. 2016;29(12):24-28.

  3. Masoumi A, Reed-Gitomer B, Kelleher C, Bekheirnia MR, Schrier RW. Developments in the management of autosomal dominant polycystic kidney disease. Ther Clin Risk Manag. 2008:4(2):393-407.